Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
SCHLEIFER LEONARD S
   2. Issuer Name and Ticker or Trading Symbol
REGENERON PHARMACEUTICALS INC [REGN] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
President & CEO
(Last)
(First)
(Middle)
777 OLD SAW MILL RIVER ROAD		 3. Date of Earliest Transaction (Month/Day/Year)
10/27/2014
(Street)

TARRYTOWN, NY 10591		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/27/2014   M(1)   6,808 A $ 304.38 48,895 D  
Common Stock 10/27/2014   F(1)   5,145 D $ 402.69 43,750 D  
Common Stock 10/27/2014   F(1)   857 D $ 402.69 42,893 D  
Common Stock 10/27/2014   M(1)   250,000 A $ 11.64 292,893 D  
Common Stock 10/27/2014   F(1)   7,226 D $ 402.69 285,667 D  
Common Stock 10/27/2014   F(1)   125,198 D $ 402.69 160,469 D  
Common Stock 10/28/2014   S(1)   12,322 D $ 400.52 (2) 148,147 D  
Common Stock 10/28/2014   S(1)   10,381 D $ 401.45 (3) 137,766 D  
Common Stock 10/28/2014   S(1)   3,318 D $ 402.54 (4) 134,448 D  
Common Stock 10/28/2014   S(1)   12,250 D $ 403.38 (5) 122,198 D  
Common Stock 10/28/2014   S(1)   2,250 D $ 404.46 (6) 119,948 D  
Common Stock 10/28/2014   S(1)   5,900 D $ 405.76 (7) 114,048 D  
Common Stock 10/28/2014   S(1)   14,052 D $ 406.5 (8) 99,996 D  
Common Stock 10/28/2014   S(1)   4,350 D $ 407.31 (9) 95,646 D  
Common Stock 10/28/2014   S(1)   2,400 D $ 408.62 (10) 93,246 D  
Common Stock 10/28/2014   S(1)   1,789 D $ 409.43 (11) 91,457 D  
Common Stock 10/28/2014   S(1)   100 D $ 410 91,357 D  
Common Stock               5,650 I By 401(k) Plan

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) $ 11.64 10/27/2014   M(1)     250,000   (12) 12/19/2015 Common Stock 250,000 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 304.38 10/27/2014   M(1)     6,808 03/18/2014 12/15/2014 Common Stock 6,808 $ 0 0 D  
Non-Qualified Stock Option (right to buy) $ 402.69 10/27/2014   A   7,226   04/27/2015(1) 12/19/2015 Common Stock 7,226 $ 0 7,226 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
SCHLEIFER LEONARD S
777 OLD SAW MILL RIVER ROAD
TARRYTOWN, NY 10591		   X     President & CEO  

Signatures

 /s/**Leonard S. Schleifer   10/29/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Disposition/acquisition made pursuant to a plan intended to comply with Rule 10b5-1(c).
(2) Represents volume-weighted average price of sales of 12,322 shares of Company stock on October 28, 2014 at prices ranging from $400.20 to $400.98. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(3) Represents volume-weighted average price of sales of 10,381 shares of Company stock on October 28, 2014 at prices ranging from $401.00 to $401.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(4) Represents volume-weighted average price of sales of 3,318 shares of Company stock on October 28, 2014 at prices ranging from $402.06 to $402.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(5) Represents volume-weighted average price of sales of 12,250 shares of Company stock on October 28, 2014 at prices ranging from $403.00 to $403.91. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(6) Represents volume-weighted average price of sales of 2,250 shares of Company stock on October 28, 2014 at prices ranging from $404.00 to $404.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(7) Represents volume-weighted average price of sales of 5,900 shares of Company stock on October 28, 2014 at prices ranging from $405.23 to $405.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(8) Represents volume-weighted average price of sales of 14,052 shares of Company stock on October 28, 2014 at prices ranging from $406.02 to $406.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(9) Represents volume-weighted average price of sales of 4,350 shares of Company stock on October 28, 2014 at prices ranging from $407.00 to $407.97. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(10) Represents volume-weighted average price of sales of 2,400 shares of Company stock on October 28, 2014 at prices ranging from $408.35 to $408.94. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(11) Represents volume-weighted average price of sales of 1,789 shares of Company stock on October 28, 2014 at prices ranging from $409.10 to $409.99. Upon request by the Commission staff, the Company, or a security holder of the Company, the reporting person will provide full information regarding the number of shares sold by the reporting person on October 28, 2014 at each separate price.
(12) The stock option award vests in four equal annual installments, commencing one year after the date of grant.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.