SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 ---------- Under the Securities Exchange Act of 1934 SCHEDULE 13G INFORMATION STATEMENT PURSUANT TO RULES 13d-1 AND 13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 IR BIOSCIENCES HOLDINGS, INC. -------------------- (Name of Issuer) Common Stock, $.001 par value per share --------------------------------------- (Title of Class of Securities) 46264M303 ------------ (CUSIP Number) August 25, 2008 ------------------------------------------------------ (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: |_| Rule 13d-1(b) |X| Rule 13d-1(c) |_| Rule 13d-1(d) Page 1 of 2 Pages SCHEDULE 13G CUSIP No. 46264M303 Page 2 of 2 Pages ------------------------------------------------------------------------------- 1) NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON BRENCOURT ADVISORS, LLC EIN # 13-4137530 ------------------------------------------------------------------------------- 2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) |_| (b) |X| ------------------------------------------------------------------------------- 3) SEC USE ONLY ------------------------------------------------------------------------------- 4) CITIZENSHIP OR PLACE OF ORGANIZATION Delaware ------------------------------------------------------------------------------- 5) SOLE VOTING POWER NUMBER 0 OF -------------------------------------------------- SHARES 6) SHARED VOTING POWER BENEFICIALLY OWNED BY 1,163,959 EACH -------------------------------------------------- REPORTING 7) SOLE DISPOSITIVE POWER PERSON WITH 0 -------------------------------------------------- 8) SHARED DISPOSITIVE POWER 1,163,959 ------------------------------------------------------------------------------- 9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,163,959 ------------------------------------------------------------------------------- 10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES |_| ------------------------------------------------------------------------------- 11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 9.98% ------------------------------------------------------------------------------- 12) TYPE OF REPORTING PERSON IA ------------------------------------------------------------------------------- CUSIP No. 46264M303 ------------------------------------------------------------------------------- 1) NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Brencourt Multi-Strategy Master, Ltd. EIN # 03-0453123 ------------------------------------------------------------------------------- 2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) |_| (b) |X| ------------------------------------------------------------------------------- 3) SEC USE ONLY ------------------------------------------------------------------------------- 4) CITIZENSHIP OR PLACE OF ORGANIZATION Bermuda ------------------------------------------------------------------------------- 5) SOLE VOTING POWER NUMBER 0 OF -------------------------------------------------- SHARES 6) SHARED VOTING POWER BENEFICIALLY OWNED BY 500,502 EACH -------------------------------------------------- REPORTING 7) SOLE DISPOSITIVE POWER PERSON WITH 0 -------------------------------------------------- 8) SHARED DISPOSITIVE POWER 500,502 ------------------------------------------------------------------------------- 9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 500,502 ------------------------------------------------------------------------------- 10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES |_| ------------------------------------------------------------------------------- 11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 4.29% ------------------------------------------------------------------------------- 12) TYPE OF REPORTING PERSON CO ------------------------------------------------------------------------------- CUSIP No. 46264M303 ------------------------------------------------------------------------------- 1) NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON MAN MAC Schreckhorn 14B Limited EIN # ------------------------------------------------------------------------------- 2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) |_| (b) |X| ------------------------------------------------------------------------------- 3) SEC USE ONLY ------------------------------------------------------------------------------- 4) CITIZENSHIP OR PLACE OF ORGANIZATION Bermuda ------------------------------------------------------------------------------- 5) SOLE VOTING POWER NUMBER 0 OF -------------------------------------------------- SHARES 6) SHARED VOTING POWER BENEFICIALLY OWNED BY 651,817 EACH -------------------------------------------------- REPORTING 7) SOLE DISPOSITIVE POWER PERSON WITH 0 -------------------------------------------------- 8) SHARED DISPOSITIVE POWER 651,817 ------------------------------------------------------------------------------- 9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 651,817 ------------------------------------------------------------------------------- 10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES |_| ------------------------------------------------------------------------------- 11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 5.59% ------------------------------------------------------------------------------- 12) TYPE OF REPORTING PERSON CO ------------------------------------------------------------------------------- CUSIP No. 46264M303 ------------------------------------------------------------------------------- 1) NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Brencourt Enhanced Multi-Strategy Dedicated Fund L.P. EIN # ------------------------------------------------------------------------------- 2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) |_| (b) |X| ------------------------------------------------------------------------------- 3) SEC USE ONLY ------------------------------------------------------------------------------- 4) CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands ------------------------------------------------------------------------------- 5) SOLE VOTING POWER NUMBER 0 OF -------------------------------------------------- SHARES 6) SHARED VOTING POWER BENEFICIALLY OWNED BY 11,640 EACH -------------------------------------------------- REPORTING 7) SOLE DISPOSITIVE POWER PERSON WITH 0 -------------------------------------------------- 8) SHARED DISPOSITIVE POWER 11,640 ------------------------------------------------------------------------------- 9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 11,640 ------------------------------------------------------------------------------- 10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES |_| ------------------------------------------------------------------------------- 11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.10% ------------------------------------------------------------------------------- 12) TYPE OF REPORTING PERSON PN ------------------------------------------------------------------------------- Schedule 13G Item 1(a). Name of Issuer: IR Biosciences Holdings, INC. Item 1(b). Address of Issuer's Principal Executive Offices: 8767 E. Via De Ventura, Suite 190 Scottsdale, AZ 85258 Item 2(a). Name of Persons Filing: Brencourt Advisors, LLC Brencourt Multi-Strategy Master, Ltd. MAN MAC Schreckhorn 14B Limited Brencourt Enhanced Multi-Strategy Dedicated Fund L.P. Item 2(b). Address of Principal Business Office or, if None, Residence: The principal office of Brencourt Advisors, LLC is: 600 Lexington Avenue 8th Floor New York, NY 10022 Item 2(c). Citizenship: Brencourt Advisors, LLC - Delaware Brencourt Multi-Strategy Master, Ltd. - Bermuda MAN MAC Schreckhorn 14B Limited - Bermuda Brencourt Enhanced Multi-Strategy Dedicated Fund L.P. - Cayman Islands Item 2(d). Title of Class of Securities: Common Stock, $0.001 par value per share Item 2(e). CUSIP Number: 46264M303 Item 3. If this statement is filed pursuant to ss.ss. 240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a: (a) |_| Broker or Dealer Registered Under Section 15 of the Act (15 U.S.C. 78o) (b) |_| Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c) (c) |_| Insurance Company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c) (d) |_| Investment Company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8) (e) |X| Investment Adviser in accordance with ss. 240.13d-1(b)(1)(ii)(E) (f) |_| Employee benefit plan or endowment fund in accordance with ss. 240.13d-1(b)(1)(ii)(F) (g) |_| Parent Holding Company or control person in accordance with ss.240.13d-1(b)(ii)(G) (h) |_| Savings Association as defined in ss.3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813) (i) |_| Church plan that is excluded from the definition of an investment company under ss.3(c)(15) of the Investment Company Act of 1940 (15 U.S.C. 80a-3) (j) |_| Group, in accordance with ss.240.13d-1(b)(ii)(J) Item 4. Ownership. (a) Amount beneficially owned: 1,163,959 (b) Percent of class: 9.98% (c) Number of shares as to which such person has: (i) Sole power to vote or to direct the vote: 0 (ii) Shared power to vote or to direct the vote: 1,163,959 (iii) Sole power to dispose or to direct the disposition of: 0 (iv) Shared power to dispose or to direct the disposition of: 1,163,959 -------------- (1) Percentages are based on 11,622,916 shares of Common Stock outstanding as of August 7, 2008 (as set forth on the Issuer's Form 10-Q, filed on August 14, 2008 with the Securities and Exchange Commission). Item 5. [ ] Ownership of Five Percent or Less of a Class. Not applicable. Item 6. Ownership of More than Five Percent on Behalf of Another Person. Various persons have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the shares of IR Biosciences Holdings, Inc. The Investment Manager is the investment advisor to MAN MAC Schreckhorn 14B Limited. Accordingly, MAN MAC Schreckhorn 14B Limited has the right to receive and the power to direct receipt of dividends from, or the proceeds from the sale of, the shares reported in the corresponding Item 9 above, which represent greater than 5% of the shares outstanding. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company. Not applicable. Item 8. Identification and Classification of Members of the Group. Not applicable. Item 9. Notice of Dissolution of Group. Not applicable. Item 10. Certification. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. SIGNATURE ---------- After reasonable inquiry and to the best knowledge and belief of the undersigned, the undersigned certifies that the information set forth in this Statement is true, complete and correct. Dated as of August 27, 2008 Brencourt Advisors, LLC By: Adam Hopkins Chief Compliance Officer By: /s/ Adam Hopkins --------------------------------------